donkey

Clinical Approach to The Dull Donkey

Citation

Alexandra K. Thiemann. February 2013. Clinical Approach to The Dull Donkey. In Practice. 35. 470-476.

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Publication date: 
1 February 2013
Journal: 
In Practice
Volume: 
35
Page numbers: 
470-476
DOI number: 
10.1136/inp.f5262
Abstract

The ‘dull donkey’ is a general descriptive term used by owners and clinicians to identify a donkey presenting with varying degrees of depression, dullness and inappetence. These cases can be frustrating to diagnose and manage successfully. This article provides an overview of the most common causes of dullness in donkeys in the UK and suggests appropriate first-line diagnostic and treatment options. It should be appreciated that, in many cases, dull donkeys may be very sick and may require high levels of intervention to recover. Such cases should be seen as priority patients.

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Quantifying the effects of individual animal characteristics and climatological factors on faecal worm egg count shedding in donkeys

Citation

Christopher J Corbett, Sandy Love, Giles T. Innocent, Ian McKendrick, Jacqui. B. Matthews, Faith A. Burden, Matthew Denwood. Quantifying the effects of individual animal characteristics and climatological factors on faecal worm egg count shedding in donkeys. Presented at British Society for Parasitology Spring Meeting.

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Date presented: 
Monday 7 April 2014
Abstract

Cyathostomins, the predominant parasitic nematodes of equids, have developed varying degrees of resistance to all three classes of anthelmintic licensed for use in horses. It is essential that the effectiveness of alternative methods of control for these pathogens are quantified, including incorporating climatic data and the commonly advocated practice of removal of faeces from pasture. Here, we obtained monthly faecal worm egg counts (FWEC, n=4,460 individual counts) from 803 donkeys based at The Donkey Sanctuary (Devon, UK). The dataset also included age, sex, field, FWEC history and previous anthelmintic administrations in each individual, as well as the pasture hygiene management method applied in the field where the donkey was grazed. FWEC were analysed alongside local climatic data using a generalised linear mixed model to assess associations between these variables and each observed monthly FWEC. The preferred model was identified using a model selection algorithm based on penalised likelihoods, and associated a 2.1% decrease in FWEC per day with air frost two calendar months ago (p<0.001) and a 38% lower FWEC in groups with twice weekly manual faecal removal compared to those with no faecal removal (p=0.004). Other weather effects, both alone and as interaction terms with the average FWEC of the field were included in the model, alongside individual FWEC history with anthelmintic administration as interaction terms and date as a single term. Our study identifies factors that may be useful as part of on-going predictive modelling based methods of improving targeted selective therapy.

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Pyrantel resistance in two herds of donkey in the UK

Citation

Edwina Lawson, Faith A. Burden, Hany Elsheikha. January 2015. Pyrantel resistance in two herds of donkey in the UK. Veterinary Parasitology.

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Publication date: 
7 January 2015
DOI number: 
10.1016/j.vetpar.2014.12.026
Abstract

Resistance to currently available anthelmintics is a serious phenomenon which is prevalent globally. Cyathostomins are one of the major parasites, and are of primary concern in donkeys. There have been reports of emerging resistance to pyrantel, but the status of pyrantel resistance in donkey populations in the UK is largely unknown. This report investigates pyrantel resistance in two geographically isolated donkey herds in the South West of England. The first herd had suspected pyrantel resistance, with already established resistance to other anthelmintics. In the second herd the efficacy of pyrantel was not suspected at the time the study took place. Faecal Egg Count Reduction Test (FECRT) was carried out, revealing large scale resistance. Eighty one percent of the first herd and 73% of the second herd had a FEC of less than 95% after treatment, and anthelmintic resistance was confirmed using the World Association for the Advancement of Veterinary Parasitology guidelines. These findings indicate that anthelmintic resistance to pyrantel exists in both tested donkey populations and illustrate the continuing development of resistance through different classes of chemotherapeutics.

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Clinical trial on the efficacy of moxidectin oral gel formulation on donkeys naturally infected by cyathostominae

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Date presented: 
Saturday 7 February 2015
Abstract

Donkeys and horses share several parasites including the small strongyles, Cyathostominae. Moxidectin (MOX), a compound of macrocyclic lactones, has a wide range of ecto and endoparasitic activity in many species. For horses, MOX is available as oral gel formulation that provides excellent and long-lasting efficacy against nematodes such as large and small strongyles. There is a paucity of data available on the efficacy of anthelmintics used in donkeys (Veneziano et al., 2011). Therapeutics, such as antiparasitic compounds, are often administered to donkeys on the basis of dosage and intervals recommended for horses, because very few drugs have donkey-specific label indications (Grosenbaugh et al., 2011). The objective of the present study was to evaluate the field efficacy and Egg Reappearance Period (ERP) of MOX oral gel up to 84 days at horse dose against natural infection of Cyathostominae in donkeys.

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Viraemic frequencies and seroprevalence of non-primate hepacivirus and equine pegiviruses in horses and other mammalian species

Citation

Sinead Lyons, Amit Kapoor, Bradley Schneider, Nathan Wolfe, Geoff Culshaw, Brendan Corcoran, Andy Durham, Faith A. Burden, Bruce McGorum, Peter Simmonds. September 2014. Viraemic frequencies and seroprevalence of non-primate hepacivirus and equine pegiviruses in horses and other mammalian species. Journal of General Virology.

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Publication date: 
5 September 2014
DOI number: 
10.1099/vir.0.065094-0
Abstract

Non-primate hepacivirus (NPHV), equine pegivirus (EPgV) and Theiler's disease associated virus (TDAV) are newly discovered members of two genera in the Flaviviridae family, Hepacivirus and Pegivirus respectively, that include human hepatitis C virus (HCV) and human pegivirus (HPgV). To investigate their epidemiology, persistence and clinical features of infection, large cohorts of horses and other mammalian species were screened for NPHV, EPgV and TDAV viraemia and for past exposure through serological assays for NPHV and EPgV-specific antibodies. NPHV antibodies were detected in 43% of 328 horses screened for antibodies to NS3 and core antibodies, of which three were viraemic by PCR. All five horses that were stablemates of a viraemic horse were seropositive, as was a dog on the same farm. With this single exception, all other species were negative for NPHV antibodies and viraemia (donkeys (n=100), dogs (n=112), cats (n=131), non-human primates (n=164) and humans (n=362). EPgV antibodies to NS3 were detected in 66.5% of horses, including 11 of the 12 horses that had EPgV viraemia. All donkey samples were negative for EPgV antibody and RNA. All horse and donkey samples were negative for TDAV RNA. By comparing viraemia frequencies in horses with and without liver disease, no evidence was obtained that supported an association between active NPHV and EPgV infections with hepatopathy. The study demonstrates that NPHV and EPgV infections are widespread and enzootic in the study horse population and confirms that NPHV and potentially EPgV have higher frequencies of viral clearance than HCV and HPgV infections in humans.

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Review of Physiological Differences Between Donkeys and Horses

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Citation

Karen Rickards. Review of Physiological Differences Between Donkeys and Horses. Presented at 2nd Donkey Welfare Symposium. (7 November - 9 November 2014). California, USA.

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Date presented: 
Saturday 8 November 2014

Control of the chewing louse Bovicola (Werneckiella) ocellatus in donkeys, using essential oils

Citation

Lauren Ellse, Faith A. Burden, Richard Wall. December 2013. Control of the chewing louse Bovicola (Werneckiella) ocellatus in donkeys, using essential oils. Medical and Veterinary Entomology. 27:4. 408-413.

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Publication date: 
1 December 2013
Volume: 
27
Issue: 
4
Page numbers: 
408-413
Abstract

Infestations by lice can be a significant clinical and welfare issue in the management of large animals. The limited range of commercial pediculicides available and the development of resistance have led to the need to explore alternative louse management approaches. The results of in vitro and in vivo trials undertaken to control populations of the donkey chewing louse, Bovicola ocellatus (Piaget) (Phthiraptera: Trichodectidae) using the essential oils of tea tree (Melaleuca alternifolia) and lavender (Lavandula angustifolia) are reported here. Results of contact and vapour bioassays showed that 5% (v/v) tea tree and lavender oils resulted in > 80% louse mortality after 2 h of exposure. On farms, separate groups of 10 donkeys sprayed with 5% (v/v) tea tree and lavender oil as part of their usual grooming regime showed significant reductions in louse numbers compared with a control group (0.2% polysorbate 80 in water). These findings indicate that tea tree and lavender essential oils can provide clinically useful levels of control of B. ocellatus when used as part of a grooming routine and suggest that with further development could form the basis of an easy to apply and valuable component of a louse management programme for donkeys.

Seasonal infestation of donkeys by lice: phenology, risk-factors and management

Citation

Lauren Ellse, Faith A. Burden, Richard Wall. April 2014. Seasonal infestation of donkeys by lice: phenology, risk-factors and management. Veterinary Parasitology.

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Publication date: 
19 April 2014
DOI number: 
10.1016/j.vetpar.2014.04.012
Abstract

A longitudinal study was undertaken over a 21 month period to examine the seasonal abundance of lice infesting donkeys, the risk factors which predispose donkeys to infestation and the effectiveness of louse management. All the lice seen were Bovicola (Werneckiella) ocellatus. A strong seasonal pattern, which was correlated with mean monthly temperature, was observed with higher prevalence and intensity in the cooler, winter months (October-March). Overall infestation in these animals was over-dispersed, suggesting that some individuals are strongly predisposed to infestation. Donkey age and mean hair length were characteristics which affected louse prevalence: older and younger donkeys and donkeys with longer hair harboured the highest numbers of lice. However, the practice of coat-clipping, to reduce the infestation, resulted in a lower louse prevalence only in the summer, suggesting that clipping is not an effective form of louse control in cooler months. Higher louse burdens were associated with larger areas of visible excoriation and hair damage, suggesting that B. ocellatus does adversely impact animal welfare. However, the ability of animal carers to estimate louse presence or absence accurately on an individual donkey was not sufficiently high to allow targeted selective treatment of heavily infested animals to be employed effectively. As animals are housed in closed herds these findings suggest that clipping in the summer and treating all animals with insecticide in late autumn, prior to turn-in may be an effective louse management strategy.

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