The detection of Bovine Papillomavirus Type 1 DNA in flies

Citation

Margaret Finlay, ZhengQiang Yuan, Faith A. Burden, Andrew F. Trawford, I. M. Morgan, M. Saveria Campo, Lubna Nasir. September 2009. The detection of Bovine Papillomavirus Type 1 DNA in flies. Virus Research. 144:1-2. 315-317.

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Publication details
Publication date: 
1 September 2009
Journal: 
Virus Research
Volume: 
144
Issue: 
1-2
Page numbers: 
315-317
DOI number: 
10.1016/j.virusres.2009.04.015
Abstract

BPVs are double stranded DNA viruses that can infect several species other than the natural host, cattle, including equids. In equids, BPV-1, and, less commonly BPV-2, infection gives rise to fibroblastic tumours of the skin. Whilst a causal relationship between BPV-1/2 and equine sarcoids is now well established, how the disease is transmitted is not known. In this study we show BPV-1 DNA can be detected in flies trapped in the proximity of sarcoid-affected animals. Sequence analysis of the BPV-1 LCR from flies indicates that flies harbour BPV-1 LCR sequence variants II and IV which are commonly detected in equine sarcoids. These data suggest that flies may be able to transmit BPV-1 between equids.

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